Antiallergic activity of loratadine a non sedating antihistamine

Histamine causes a chain reaction that results in allergic symptoms such as itchy eyes, sneezing and a runny nose.Loratadine blocks histamine receptors and so stops this chain reaction.Two hundred and ten patients with chronic urticaria were divided into two groups; one group was treated with Loratadine 10mg daily while the other with cetirizine 10mg daily. Pretreatment and post-treatment evaluations were made. It was noticed that loratadine was superior to cetirizine in terms of a rapid onset of actions, overall clinical efficacy and minimal side effects.

Patients with intermittent symptoms are often treated adequately with oral antihistamines, decongestants, or both as needed.

Loratadine can also be used to relieve the symptoms of a condition called chronic idiopathic urticaria.

This is a chronic itchy rash, similar to nettle rash, but with no apparent cause.

Adults and children over 12 years of age : One Encilor tablet once daily.

It is usually administered in the morning or when symptoms require treatment.

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